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Glenn J Bubley Selected Research

Hormones (Hormone)

1/2021Results of a Randomized Phase II Trial of Intense Androgen Deprivation Therapy prior to Radical Prostatectomy in Men with High-Risk Localized Prostate Cancer.
1/2021Outcomes of Post-Neoadjuvant Intense Hormone Therapy and Surgery for High Risk Localized Prostate Cancer: Results of a Pooled Analysis of Contemporary Clinical Trials.
10/2019Evaluation of Intense Androgen Deprivation Before Prostatectomy: A Randomized Phase II Trial of Enzalutamide and Leuprolide With or Without Abiraterone.
11/2017Expression of PD-L1 in Hormone-naïve and Treated Prostate Cancer Patients Receiving Neoadjuvant Abiraterone Acetate plus Prednisone and Leuprolide.
5/2008A phase II study of mifepristone (RU-486) in castration-resistant prostate cancer, with a correlative assessment of androgen-related hormones.
3/2008Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group.
2/2008A phase 2 study of carboplatin plus docetaxel in men with metastatic hormone-refractory prostate cancer who are refractory to docetaxel.
6/2006Celecoxib versus placebo for men with prostate cancer and a rising serum prostate-specific antigen after radical prostatectomy and/or radiation therapy.
3/2006Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer.

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Glenn J Bubley Research Topics

Disease

52Prostatic Neoplasms (Prostate Cancer)
01/2021 - 07/2002
31Neoplasms (Cancer)
01/2021 - 07/2002
7Neoplasm Metastasis (Metastasis)
01/2021 - 03/2006
6Residual Neoplasm
01/2021 - 11/2014
5Disease Progression
02/2017 - 02/2008
3Hypoxia (Hypoxemia)
08/2008 - 12/2006
2Diarrhea
02/2012 - 02/2005
1Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
01/2021
1Carcinoma (Carcinomatosis)
01/2021
1Urogenital Neoplasms
01/2021
1Kidney Neoplasms (Kidney Cancer)
01/2021
1Pathologic Complete Response
05/2017
1Vaccinia
09/2015
1Fowlpox
09/2015
1Exanthema (Rash)
02/2012
1Circulating Neoplastic Cells
03/2010
1Hyperaldosteronism (Conn Syndrome)
03/2010
1Hypertension (High Blood Pressure)
03/2010
1Hypokalemia
03/2010
1Renal Cell Carcinoma (Grawitz Tumor)
08/2008
1Pain (Aches)
03/2008
1Febrile Neutropenia
02/2008

Drug/Important Bio-Agent (IBA)

28AndrogensIBA
01/2021 - 07/2002
15Androgen Receptors (Androgen Receptor)IBA
01/2021 - 07/2002
9Prostate-Specific Antigen (Semenogelase)IBA
01/2021 - 01/2003
9Hormones (Hormone)IBA
01/2021 - 03/2006
7enzalutamideIBA
01/2021 - 01/2017
6Docetaxel (Taxotere)FDA Link
01/2020 - 12/2006
6abirateroneIBA
10/2019 - 10/2011
6Leuprolide (Lupron)FDA LinkGeneric
10/2019 - 11/2014
6Biological ProductsIBA
07/2017 - 05/2004
6Proteins (Proteins, Gene)FDA Link
09/2007 - 11/2002
5Abiraterone AcetateIBA
01/2018 - 03/2010
4Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2003
4Prednisone (Sone)FDA LinkGeneric
10/2019 - 03/2010
4Dutasteride (Avodart)FDA Link
05/2017 - 11/2009
3Androgen Antagonists (Antiandrogens)IBA
01/2021 - 05/2008
3Testosterone (Sustanon)FDA Link
01/2021 - 03/2006
3PlatinumIBA
01/2021 - 02/2008
3DNA (Deoxyribonucleic Acid)IBA
01/2019 - 05/2005
2Pharmaceutical PreparationsIBA
01/2020 - 03/2008
2Ketoconazole (Nizoral)FDA LinkGeneric
03/2015 - 11/2009
2RNA (Ribonucleic Acid)IBA
01/2015 - 11/2009
2Messenger RNA (mRNA)IBA
01/2015 - 09/2007
2Sirolimus (Rapamycin)FDA Link
08/2008 - 02/2007
2Celecoxib (Celebrex)FDA Link
06/2006 - 01/2005
2Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
06/2006 - 01/2005
1Immune Checkpoint InhibitorsIBA
01/2021
1NivolumabIBA
01/2021
1IpilimumabIBA
01/2021
1taxaneIBA
01/2020
1cabazitaxelFDA Link
01/2020
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
10/2019
1Cell-Free Nucleic AcidsIBA
01/2019
1Circulating Tumor DNAIBA
01/2019
1AntibodiesIBA
11/2017
1GP 4 (GP4)IBA
07/2017
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
05/2017
13- hydroxy- 17- (1H- benzimidazole- 1- yl)androsta- 5,16- dieneIBA
01/2017
1Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2017
1PROSTVACIBA
09/2015
1VaccinesIBA
09/2015
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
09/2015
1Bevacizumab (Avastin)FDA Link
08/2015
1Flutamide (Eulexin)FDA LinkGeneric
03/2015
1ProgesteroneFDA LinkGeneric
03/2015
1MicroRNAs (MicroRNA)IBA
01/2015
1Cisplatin (Platino)FDA LinkGeneric
06/2014
1Vinblastine (Vinblastine Sulfate)FDA Link
06/2014
1Methotrexate (Mexate)FDA LinkGeneric
06/2014
1pegfilgrastim (Neulasta)FDA Link
06/2014
1Doxorubicin (Adriamycin)FDA LinkGeneric
06/2014
1Lapatinib (GW572016)FDA Link
02/2013
1Epidermal Growth Factor (EGF)IBA
02/2013
1vandetanib (ZD6474)IBA
02/2012
1SteroidsIBA
10/2011
1LigandsIBA
03/2010
1MineralocorticoidsIBA
03/2010
1Hydrocortisone (Cortisol)FDA LinkGeneric
11/2009
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
11/2009
1DNA ProbesIBA
11/2009
1AntigensIBA
09/2009
1Transcription Factors (Transcription Factor)IBA
09/2009
1Silybin (Lagosa)IBA
12/2008
1ElementsIBA
08/2008
1endothelial PAS domain-containing protein 1IBA
08/2008
1Firefly LuciferasesIBA
08/2008
1Mifepristone (RU 486)FDA Link
05/2008
1Carboplatin (JM8)FDA LinkGeneric
02/2008

Therapy/Procedure

28Therapeutics
01/2021 - 07/2002
14Prostatectomy (Retropubic Prostatectomy)
01/2021 - 11/2002
13Castration
01/2021 - 03/2008
4Drug Therapy (Chemotherapy)
02/2012 - 02/2005
3Radiotherapy
01/2021 - 06/2006
2Neoadjuvant Therapy
01/2021 - 05/2017
2Lasers (Laser)
02/2013 - 03/2006
1Aftercare (After-Treatment)
01/2017
1Brachytherapy
06/2013
1Conservative Treatment
02/2013
1Immunotherapy
09/2009